This book is essential reading for those interested in understanding current research trends in biomechanics at micro- and nanoscale levels. It details the research carried out to date in this field by fourteen prominent researchers as part of a four-year government supported project which commenced in 2003. The coverage includes four broad areas: cell mechanics, cell response to mechanical stimulation, tissue engineering, and computational biomechanics.

Contents:

• Heterogeneous Expression of the Motor Protein Prestin of Cochlear Outer Hair Cells (H Wada et al.)
• Effects of Actin Filaments on Anisotropy and Stiffness of Aortic Smooth Muscle Cells (T Matsumoto & K Nagayama)
• Micro-Vessel Network Formation of Endothelial Cells with in Vitro Three Dimensional Model (K Tanishita et al.)
• Time-Dependent Mechanical Behaviors of Articular Cartilage and Chondrocytes Under Constant Total Compressive Deformation (T Murakami et al.)
• Threshold Fiber Strain That Induces Reorganization of Cytoskeletal Actin Structure in Osteoblastic Cells (T Adachi & K Sato)
• Morphology of Endothelical Cells in Response to Hydrostatic Pressure (M Sato)
• Mechanosensing in Intestinal Villi: ATP Signaling in Subepithelial Fibroblasts Network (K Furuya et al.)
• Microelements for Cartilage Tissue Engineering (K Tsuchiya et al.)
• Interrelationship Between Water Filtration Velocity and the Thicknesss of Pseudointima Formed at the Wall of Artificial Vascular Grafts Implanted in the Dog Common Carotid Artery (T Karino et al.)
• Strengthening of Fibrous Tissues Under Mechanical Stimuli (K Takakuda)
• Assessment of Cortical Bone Microstructure Using Monochromatic Synchrotron Radiation Micro-CT (T Matsumoto et al.)
• Study on Particle Presentations of Blood Cells and the Plasma in Microvascular Blood Flow (T Yamaguchi et al.)
• Brief Reviews of Mechanical Models of Skeletal Muscle and Formulation of a Muscle Model Taking into Acount Microstructure and Damage (E Tanaka & D Ito)
• Numerical Stimulation of the Effects of Actin Binding and Cellular Deformation on the Orientation of Actin Stress Fibers Under Cyclic Stretch (H Yamada et al.)

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